Manscript Submission

IN VITRO ANTHELMINTIC ACTIVITY OF ERVATAMIA CORONARIA AGAINST HAEMONCHUS CONTORTUS

The objective of the study is to evaluate the in vitro anthelmintic activity of Ervatamia coronaria leaves in comparison with anthelmintic drug levamisole. The in vitro anthelmintic activity of aqueous leaf extract of Ervatamia coronaria were conducted on mature live Haemonchus contortus of sheep. The inhibition of motility of the worms kept in the aqueous leaf extract of Ervatamia coronaria, which was used as the criterion for anthelmintic activity. Levamisole was used as reference standard. The aqueous leaf extract of Ervatamia coronaria, exhibited anthelmintic activity against Haemonchus contortus as evident from the mortality of the worms and its effect was comparable with levamisole. It was concluded that aqueous leaf extract of Ervatamia coronaria, exhibited anthelmintic activity against Haemonchus contortus isolated from sheep. Further studies on Ervatamia coronaria is required to identify the active principle responsible for anthelmintic activity