Manscript Submission

A REVIEW ON STANDARDISATION OF HERBAL FORMULATION

Arun Rasheed
Department of Pharmacognosy and Phytochemistry, Sree Vidyanikethan College of Pharmacy, A. Rangampet, Tirupati, Andhra Pradesh, India.
Sravya Reddy B
Department of Pharmacognosy and Phytochemistry, Sree Vidyanikethan College of Pharmacy, A. Rangampet, Tirupati, Andhra Pradesh, India.
Roja C
Department of Pharmacognosy and Phytochemistry, Sree Vidyanikethan College of Pharmacy, A. Rangampet, Tirupati, Andhra Pradesh, India.

WHO ,Herbal formulation ,Standardization ,Quality control ,Nanoherbal drugs ,Phytosomes ,DNA markers ,

Herbal medicines are not a simple task since many factors influence the biological efficacy and reproducible therapeutic effect. Standardized herbal products of consistent quality and containing well-defined constituents are required for reliable clinical trials and to provide consistent beneficial therapeutic effects. Pharmacological properties of an herbal formulation depend on phytochemial constituents present therein. Development of authentic analytical methods which can reliably profile the phytochemical composition, including quantitative analyses of market/bioactive compounds and other major constituents, is a major challenge to scientists. An overview covering various techniques employed in extraction and characterization of herbal medicines as well as herbal nanomedicines standardization is reported. In addition, phytosomes increased bioavailability, bhasma as ametal nanobarrier drug delivery system, potential of metabolomics in the development of improved phytotherapeutic agents, DNA based molecular markers in adulterants, and SCAR markers for authentification and discrimination if herbs from their adulterants are reported. Nanotechnology based herbal drugs possess improved solubility and enhanced bioavailability.

2 , 2 , 2012

74 - 88