IN VITRO ANTHELMINTIC ACTIVITY OF ERVATAMIA CORONARIA AGAINST HAEMONCHUS CONTORTUS
Aleemullah MF
Department of Microbiology, Madha Medical College and Research Institute, Chennai, India
Arshad Akeel C
Consultant Physician, Apollo Hospitals, Greams Road, Chennai, India
Balamuruganvelu S
Department of Microbiology, Sri Lakshmi Narayanan Institute of Medical Sciences, Pondicherry, India
Latha M
Department of Oral Pathology, K.G.F College of Dental Science, D.K Plantations, BEML Nagar , K.G.F Kolar, India
Jaikumar S
Department of Pharmacology, Sri Lakshmi Narayanan Institute of Medical Sciences, Pondicherry, India
Sengottuvelu S
Department of Pharmacology, Nandha College of Pharmacy, Erode, India
The objective of the study is to evaluate the in vitro anthelmintic activity of Ervatamia coronaria leaves in comparison with anthelmintic drug levamisole. The in vitro anthelmintic activity of aqueous leaf extract of Ervatamia coronaria were conducted on mature live Haemonchus contortus of sheep. The inhibition of motility of the worms kept in the aqueous leaf extract of Ervatamia coronaria, which was used as the criterion for anthelmintic activity. Levamisole was used as reference standard. The aqueous leaf extract of Ervatamia coronaria, exhibited anthelmintic activity against Haemonchus contortus as evident from the mortality of the worms and its effect was comparable with levamisole. It was concluded that aqueous leaf extract of Ervatamia coronaria, exhibited anthelmintic activity against Haemonchus contortus isolated from sheep. Further studies on Ervatamia coronaria is required to identify the active principle responsible for anthelmintic activity
4 , 4 , 2014
167 - 168