CHEMICAL COMPOSITION AND ANTIBACTERIAL ACTIVITY OF THE LEAF OIL OF THYMUS VULGARIS L
Tsige Reda
Department of Chemistry, College of Natural and Computational Sciences, Mekelle University, Ethiopia
C.R.Unnithan
Department of Chemistry, College of Natural and Computational Sciences, Mekelle University, Ethiopia
Kebede Taye
Department of Chemistry, College of Natural and Computational Sciences, Mekelle University, Ethiopia
Legesset Brhane
Department of Chemistry, College of Natural and Computational Sciences, Mekelle University, Ethiopia
The constituents of the leaf oil extracted by hydro distillation of Thymus vulgaris L, family, Lamiaceae from Ethiopia was examined by GC-MS. The yield of the yellowish oil was found to be be 0.97 % (w/w) in relation to dry weight basis. Eighteen chemical constituents were identified accounting for cent percent the leaf oil. The major terpenoids identified were thymol (31.977%), o-cymene (29.992%), carvacrol (14.541%), ç-terpinene (9.079%), linalyl anthranilate (4.762%), α-terpinene (1.756%) and 4-terpineol (1.464%). The leaf oil of Thymus vulgaris showed remarkable antibacterial activity against both gram negative (Escherichia coli) and gram positive (Staphylococcus aureus) bacteria.
5 , 1 , 2015
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