40EVALUATION OF LARVICIDAL ACTIVITY OF VERNONIA ADOENSIS LEAVES AGAINST CULEX QUINGUEFASCIATUSThe study was conducted to investigate the larvicidal activity of Vernonia adoensis leaves methanol - water extract against Culex quinquefasciatus. The plant samples were extracted using methanol and water in the ratio 9:1. From the study the leaves of Vernonia adoensis were found to have toxicity against Culex quinguefasciatus with a percentage mortality of 80% at a concentration of 2000 mg/l, 60% at a concentration of 1000 mg/l, 40% concentration of 500 mg/l and 20% concentration of 250 mg/l. The results from this study shows that Vernonia adoensis leaves extract can be used as a potential insecticide against Culex quinquefasciatus. More research needs to be done to analyze the specific compounds in the plant which are acting against the larvae.drtanthony2011@yahoo.comResearch412014 Larvicidal activity,Vernonia adoensis,Culex quinguefasciatusMutuku Chrispus Ngule,T. Anthoney Swamy,Richard MachokaDepartment of Chemistry, University of Eastern Africa Baraton, P.O. Box 2500 - 30100, Eldoret, Kenya,Department of Chemistry, University of Eastern Africa Baraton, P.O. Box 2500 - 30100, Eldoret, Kenya,Department of Biology, University of Eastern Africa Baraton, P.O. BOX 2500-30100, Kenya